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. 2016 Oct 4;214(Suppl 3):S326–S332. doi: 10.1093/infdis/jiw250

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Figure 1. — Humoral responses in individual guinea pigs after adenovirus type 5 (Ad5) Ebola virus (EBOV) variant Makona glycoprotein (MakGP) vaccination and survival and weight change after guinea pig–adapted EBOV challenge. Concentrations of EBOV GP–specific antibodies were measured in guinea pig sera harvested weekly 0–4 weeks after vaccination. Immunoglobulin G (IgG; A) and immunoglobulin M (IgM; B) for vaccinated animals. Survival (C) and weight loss (D) for vaccinated animals. Titers were expressed as reciprocal dilutions of IgG or IgM. LacZ, control guinea pigs that received recombinant Ad5 expressing lacZ.