Table 2.
Clinical Performance | qRT-PCR Positivea | qRT-PCR Negative | Total |
---|---|---|---|
RDT positive | 72b | 2 | 74 |
RDT negative | 44c | 58 | 102 |
Total | 116 | 60 | 176 |
Proportion | Percentage (95% CI) |
||
PPA | 72/116 | 62.1 (52.6–70.9) | |
NPA | 58/60 | 96.7 (88.5–99.6) | |
PPV | 72/74 | 97.3 (90.6–99.7) | |
NPV | 58/102 | 56.9 (46.7–66.6) | |
Accuracy | 130/176 | 73.9 (66.9–79.8) |
The diagnostic likelihood was 18.6 (P < .0001).
Abbreviations: CI, confidence interval; Ct, cycle threshold; NPA, negative percentage agreement; NPV, negative predictive value; PPA, positive percentage agreement; PPV, positive predictive value; qRT-PCR, quantitative reverse transcription–polymerase chain reaction; RDT, rapid diagnostic test.
a A Ct value of <45 was considered positive.
b RDT true-positive Ct range, 19.6–29.1.
c RDT false-negative Ct range, 33.6–40.2.