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. 2016 Oct 5;6:34504. doi: 10.1038/srep34504

Figure 3. MiR-204 represses cell proliferation, growth and migration.

Figure 3

(A,B) MTT assays of MDA-MB-231 (A) and MCF-7 cells (B) transfected with pre-miR-204 (30 nM) or pre-miR-negative control (scramble) at 48 h and 24 h post-transfection. (C,D) Graphical representation of colony-forming assays for MDA-MB-231 (C) and MCF-7 cells (D) transfected with pre-miR-204 or scramble. (E,F) Scratch/wound-healing assays of MDA-MB-231 (E) and MCF-7 (F) cell monolayers treated with pre-miR-204 (30 nM), or scramble for 12 h and 24 h. (G,H) Transwell cell migrating assays of MDA-MB-231 (G) and MCF-7 (H) cells treated as above. (I) Matrigel invasion assays of MDA-MB-231 cells transfected with pre-miR-204 (30 nM). Results shown are the mean of three independent experiments +/− SD. *p < 0.05, **p < 0.01 and ***p < 0.001 compared to controls. Bars represent the mean of three independent experiments ± S.D.