Table 1. Summary of statistical tests for performance of nQi (main contribution of this paper), alternating finger tapping, single key tapping and typing speed on the combined dataset of 42 PD subjects and 43 controls.
| Parkinson’s | Controls | StatisticalSignificance (unadjusted) | StatisticalSignificance (adjusted) | |
|---|---|---|---|---|
| n (total n = 85) | 42 | 43 | ||
| Avg. UPDRS-III (std) | 20.6 (7.7) | 1.9 (1.8) | ***(p < 0.001) | N/A |
| Avg. nQi (std) | 0.130 (0.085) | 0.060 (0.057) | ***(p < 0.001) | ***(p = 0.001)a |
| Avg. Alternating Finger Tapping (std) | 95.37 (22.01) | 128.37 (28.85) | ***(p < 0.001) | ***(p < 0.001)b |
| Avg. Single Key Tapping (std) | 162.88 (24.09) | 170.85 (16.45) | not sig. (p = 0.08) | *(p = 0.035)b |
The unadjusted statistical significance is computed with two-sided Mann-Whitney U test.
aAn additional co-variate, typing speed, was added for nQi. nQi and alternating finger tapping are the two tests that show a consistent statistical significance difference between PD subjects and controls. In the adjusted model for nQi, none of the co-variates reached statistical significance (see supplementary materials). For completeness, we also show the UPDRS-III scores. In our datasets, only subjects with confirmed clinical PD or lack thereof were included. Therefore, UPDRS-III, which is based on clinical evaluations, can discriminate PD subjects from controls perfectly.
bThe adjusted significance tests were computed with logistic regression models including sex, age and years of education as co-variates.