Table 1. Results of the prognostic value of platelet to lymphocyte ratio (PLR) for the survival of 1388 patients with lung cancer.
Number of patients | OS | PFS | |||||||
---|---|---|---|---|---|---|---|---|---|
Univariate | Multivariate | Univariate | Multivariate | ||||||
HR | p | HR | p | HR | p | HR | p | ||
all patients | 1388 | 1.451(1.187–1.774) | <0.001 | 1.405(1.147–1.722) | 0.001 | 1.446(1.183–1.768) | <0.001 | 1.384(1.130–1.695) | 0.002 |
sex | |||||||||
male | 982 | 1.685(1.346–2.109) | <0.001 | 1.700(1.353–2.136) | <0.001 | 1.676(1.339–2.098) | <0.001 | 1.651(1.314–2.074) | <0.001 |
female | 406 | 0.894(0.566–1.412) | 0.632 | 0.709(0.446–1.127) | 0.146 | 0.896(0.568–1.414) | 0.637 | 0.728(0.458–1.155) | 0.178 |
age | |||||||||
>65 | 373 | 1.665(1.195–2.321) | 0.003 | 1.635(1.166–2.292) | 0.004 | 1.665(1.195–2.320) | 0.003 | 1.650(1.174–2.318) | 0.004 |
≤65 | 1015 | 1.323(1.027–1.704) | 0.031 | 1.280(0.990–1.653) | 0.059 | 1.317(1.022–1.696) | 0.033 | 1.249(0.967–1.613) | 0.088 |
stage | |||||||||
I/II | 933 | 1.550(1.186–2.024) | 0.001 | 1.502(1.148–1.965) | 0.003 | 1.548(1.185–2.022) | 0.001 | 1.512(1.155–1.979) | 0.003 |
III/IV | 455 | 1.237(0.925–1.655) | 0.152 | 1.318(0.979–1.774) | 0.069 | 1.187(0.887–1.587) | 0.248 | 1.256(0.934–1.688) | 0.131 |
cancer type | |||||||||
NSCLC | 1292 | 1.462(1.184–1.804) | <0.001 | 1.393(1.125–1.724) | 0.002 | 1.462(1.185–1.804) | <0.001 | 1.380(1.115–1.707) | 0.003 |
SCLC | 96 | 1.412(0.719–2.776) | 0.317 | 1.393(0.703–2.758) | 0.342 | 1.343(0.683–2.639) | 0.393 | 1.298(0.655–2.571) | 0.454 |
P < 0.05 is considered to be significant. Abbreviation: HR: hazard ration, NSCLC: non-small cell lung cancer; SCLC: small cell lung cancer, OS: overall survival; PFS: progression free survival.