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. 2016 Oct 5;6:34790. doi: 10.1038/srep34790

Figure 3. Gallic acid attenuates concentric cardiac hypertrophy in isoproterenol (ISP)-treated mice.

Figure 3

(A) Representative M-mode echocardiograms are shown. Gallic acid administration was started 1 week before infusion of ISP in mice; sham + vehicle, sham + gallic acid, ISP + vehicle, and ISP + gallic acid group. White arrows and yellow arrows indicate the left ventricular posterior wall thickness and septum thickness, respectively. (B) Left ventricular posterior wall thickness (mm) (C) Interventricular septum thickness (mm). (D) Left ventricular end-systolic dimension (mm). (E) Left ventricular end-diastolic dimension (mm). (F) Fractional shortening (%). Data are presented as the means ± SD of 8 mice per group. (G) Systolic blood pressure was determined 2 weeks after ISP infusion. *P < 0.05 and ***P < 0.001 versus sham + vehicle; #P < 0.05 versus ISP + vehicle. NS indicates not significant.