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(A) The natural level of both serotonin quantity and HTRs expression ensure the normal serotonin signal. (B) During embryo early development, to maintain the regular serotonin signal, fewer HTRs express reply more available serotonin resulting from SSRIs that are taken by depressed pregnant. (C) Lower serotonin signal appears after the stop using of SSRIs as the fewer HTRs expression.
