Table 4.
Rhupus (n = 9) | JA (n = 10) | NDNE (n = 7) | Rhupus vs JA (p value) | Rhupus vs NDNE (p value) | JA vs NDNE (p value) | |
---|---|---|---|---|---|---|
Age, years (mean ± SD) | 41.0 ± 5.7 | 61.3 ± 14.3 | 43.1 ± 16.4 | 0.001 | 0.765 | 0.035 |
Disease duration, years (mean ± SD) | 13.7 ± 6.6 | 21.7 ± 10.7 | 10.8 ± 4.1 | 0.035 | 0.298 | 0.003 |
Rheumatoid factor | 7 (77.8 %) | 2 (20.0 %) | 2 (28.5 %) | - | - | - |
Anti-CCP | 6 (66.7 %) | 0 (0) | 1 (14.2 %) | - | - | - |
US erosion number (median (25th to 75th percentile)) | 3.0 (1.7–4.2) | 0.5 (0–2.0) | 0 (0–1.0) | 0.019 | 0.004 | 0.569 |
US quadrants with erosion | 27 (10.7 %) | 12 (4.3 %) | 4 (2.0 %) | - | - | - |
ScUSSe total (median (25th to 75th percentile)) | 4.0 (2.5–6.0) | 1.0 (0–3.0) | 0 (0–1.0) | 0.021 | 0.003 | 0.535 |
Grade 1 (<2 mm) | 16a | 10a | 4a | - | - | - |
Grade 2 (2–3 mm) | 9a | 1a | 0a | - | - | - |
Grade 3 (>3 mm) | 2a | 1a | 0a | - | - | - |
CT erosion number (mean ± SD) | 14.0 ± 9.7 | 5.7 ± 5.1 | 4.7 ± 4.5 | 0.050 | 0.030 | 0.543 |
RAMRIS (mean ± SD) | 21.6 ± 18.2 | 7.4 ± 7.0 | 5.1 ± 5.0 | 0.053 | 0.029 | 0.448 |
RAMRIS MCP (median (25th to 75th percentile)) | 6.0 (4.5–10.2) | 1.0 (0–2.0) | 0 (0–1.5) | 0.013 | 0.009 | 0.353 |
RAMRIS wrist (median (25th to 75th percentile)) | 8.0 (10.2–16.2) | 3.5 (0–11.0) | 3.0 (0.5–6.7) | 0.111 | 0.057 | 0.694 |
Grade 1 (1–10 %) | 24a | 21a | 6a | - | - | - |
Grade 2 (11–20 %) | 19a | 6a | 6a | - | - | - |
Grade 3 − 10 (21–100 %) | 7a | 1a | 2a | - | - | - |
Numbers in bold indicate statistical significance for p <0.05. Boxes are empty where statistics was not applied
aAbsolute numbers referring to joint quadrants. JA Jaccoud’s arthropathy, NDNE non-deforming non-erosive, Anti-CCP anti-cyclic citrullinated peptide, US ultrasound, ScUSSe scoring ultrasound structural erosion, CT computed tomography, RAMRIS rheumatoid arthritis magnetic resonance imaging score, MCP metacarpophalangeal joint