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. 2016 Oct 5;17:405. doi: 10.1186/s12859-016-1283-3

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Evaluation of combination strategy for particle picking. a Comparison of precision and recall curves when using individual scaling factors or a combination of scaling factors in particle picking for tomograms (crowding level 1, SNR = 50). b Comparison of F-scores for particle picking with individual or a combination of scaling factors. c Comparison of the number of true positives detected in particle picking when using the single optimal scaling factor (σ = 7) and a combination of scaling factors (σ = 7, 5, 9) for complexes of different size. The barplot shows the number of true positives (reliably detected particles) and the ground truth copy numbers for differently sized complexes (small, medium, large)