Table 5.
Univariate and multivariate analyses evaluating the association of hyperchloremia-48 on 30-day mortality
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| OR (95 % CI) | p value | OR (95 % CI) | p value | |
| Age (per year) | 1.014 (0.994–1.034) | 0.17 | . | |
| ISS | 1.080 (1.033–1.130) | 0.001 | . | |
| RTS | 0.621 (0.511–0.754) | <0.001 | 0.715 (0.551–0.929) | 0.01 |
| Mechanical ventilation (yes) | 21.838 (2.929–162.842) | 0.003 | . | |
| Transfusion (yes) | 6.750 (2.290–19.894) | 0.001 | . | |
| Hypotension (SBP < 90, yes) | 4.477 (1.971–10.168) | <0.001 | . | |
| Hypothermia (BT < 35 °C, yes) | 3.828 (1.626–9.012) | 0.002 | . | |
| Cumulative fluid balance at 48 h (per L) | 1.000 (1.000–1.000)a | 0.01 | . | |
| Base deficit at 48 h (per 1mmol/L) | 0.740 (0.631–0.868) | <0.001 | 0.782 (0.650–0.940) | 0.009 |
| Hyperchloremia-48 (yes) | 8.667 (3.736–20.103) | <0.001 | 4.567 (1.634–12.764) | 0.004 |
| Use of vasopressor (yes) | 29.186 (6.789–125.472) | <0.001 | 9.233 (1.925–44.295) | 0.005 |
| Use of loop diuretics (yes) | 3.243 (1.432–7.344) | 0.005 | . | |
| AKI (yes) | 7.130 (3.112–16.336) | <0.001 | 2.574 (0.650–0.940) | 0.08 |
OR odds ratio, CI confidence interval, ISS injury severity score, RTS revised trauma score, AKI acute kidney injury, SBP systolic blood pressure, BT body temperature, AKI acute kidney injury
a(1.000027–1.000216)
p value for the Hosmer-Lemeshow goodness-of-fit-test was 0.256