Table 7.
Univariate and multivariate analyses evaluating the association of Δchloride (mmol/L) on 30-day mortality
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| OR (95 % CI) | p value | OR (95 % CI) | p value | |
| Age (per year) | 1.014 (0.994–1.034) | 0.17 | . | |
| ISS | 1.080 (1.033–1.130) | 0.001 | . | |
| RTS | 0.621 (0.511–0.754) | <0.001 | 0.728 (0.559–0.950) | 0.02 |
| Mechanical ventilation (yes) | 21.838 (2.929–162.842) | 0.003 | . | |
| Transfusion (yes) | 6.750 (2.290–19.894) | 0.001 | . | |
| Hypotension (SBP < 90mmHg, yes) | 4.477 (1.971–10.168) | <0.001 | . | |
| Hypothermia (BT < 35 °C, yes) | 3.828 (1.626–9.012) | 0.002 | . | |
| Cumulative fluid balance at 48 h (per L) | 1.000 (1.000–1.000)a | 0.01 | . | |
| Base deficit at 48 h (per 1 mmol/L) | 0.740 (0.631–0.868) | <0.001 | 0.761 (0.631–0.918) | 0.004 |
| Δchloride (per 1 mmol/L) | 1.165 (1.096–1.238) | <0.001 | 1.096 (1.027–1.169) | 0.006 |
| Use of vasopressor (yes) | 29.186 (6.789–125.472) | <0.001 | 10.392 (2.222–48.604) | 0.003 |
| Use of loop diuretics (yes) | 3.243 (1.432–7.344) | 0.005 | . | |
| AKI (yes) | 7.130 (3.112–16.336) | <0.001 | . | |
OR odds ratio, CI confidence interval, ISS injury severity score, RTS revised trauma score, AKI acute kidney injury, SBP systolic blood pressure, BT body temperature, AKI acute kidney injury
a(1.000027–1.000216)
p value for the Hosmer-Lemeshow goodness-of-fit-test was 0.835