Table 2.

Effects of fat-enriched diet on the development of MetS

Researchers (Year)	Types of diet	Treatment length	Strains of animal	Components of metabolic syndrome
				Obesity	Hyperglycemia	Hypertension	Dyslipidemia
Dobrian et al. [110]	High-fat diet	10 weeks	Male Sprague-Dawley rats	✓	-	✓	✓
Ghibaudi et al. [59]	High-fat diet	24 weeks	Male Sprague-Dawley weanling rats	✓	✓	-	✓
Rossmeisl et al. [111]	High-fat diet	8 weeks	Male C57BL/6 J mice	✓	✓	-	✓
			Male AKR/J (AKR) mice	✓	✓	-	✓
Gallou-Kabani et al. [112]	High-fat diet (60 %)	20 weeks	Male & female C57Bl/6 J mice	✓	✓	-	✓
			Male & female A/J mice	✓	✗	-	✓
Fraulob et al. [60]	High-fat diet	16 weeks	Male C57BL/6 mice	✓	✓	-	✓
Graham et al. [61]	High-fat diet	40 weeks	Male C57BL/6 mice	-	-	-	✓
Halade et al. [56]	High-fat diet	24 weeks	Female C57Bl/6 J mice	✓	-	-	-
Davidson et al. [113]	High-fat diet	24 weeks	Male Sprague-Dawley rats	✓	✓	-	✓
Pirih et al. [114]	High-fat diet	13 weeks	C57BL/6 mice (wild type)	-	✗	-	✓
			Hyperlipidemic (Ldlr−/−) mice	-	✓	-	✓
Podrini et al. [115]	High-fat diet	12 weeks	Female C57BL/6NTac mice	✓	✓	-	✓
Xu et al. [57]	High-fat diet	12 weeks	Male C57BL/6 mice	✓	-	-	-
Fujita and Maki [24]	High-fat diet	4 weeks	Male C57BL/6 J mice	✓	-	-	✓
Gancheva et al. [116]	High-fat diet	8 weeks	Male Wistar rats	✓	✓	-	✓
Li et al. [62]	High-fat diet	16 weeks	Male C57BL/6 mice	✓	✓	-	✓
Suman et al. [23]	High-fat diet	10 weeks	Male Wistar rats	✓	✓	✓	✓

Table represents the effects of fat-enriched diet on each component of MetS. The symbol ‘✓’ and ‘✗’ indicate the presence and absence of significant effect of the sign of MetS respectively, while ‘-’ indicates the effects on the component not being evaluated in the study