Table 5.
Relative risks (RR) for Multiple Organ Dysfunction Syndrome (MODS) and mortality among patients with scrub typhus in a hospital of Meghalaya, India, Sept 2011–Aug 2012 (n = 90)
| Study variable | MODS (n = 13) | Mortality (n = 5) | ||||
|---|---|---|---|---|---|---|
| RR | 95 % CI | p | RR | 95 % CI | p | |
| Gender (female vs. male) | 1.3 | 0.46–3.5 | 0.637 | 12 | 0.68–210.8 | 0.637 |
| Presence of eschar | 2.4 | 0.79–7.28 | 0.122 | 2.0 | 0.25–16.17 | 0.515 |
| Fever (<7 days vs. >7 days) | 2.4 | 0.34–17.1 | 0.38 | 2.32 | 0.14–39.8 | 0.562 |
| Occupation (farmer / labourer vs. others) | 0.45 | 0.13–1.52 | 0.199 | 1.0 | 0.17–5.69 | 1.00 |
| Age (≥60 years vs. <60 years) | 1.63 | 0.43–6.24 | 0.471 | 2.25 | 0.2–18.02 | 0.44 |
| Serum Bilirubin >3 mg/dl | 16.16 | 5.97–43.7 | <0.001* | 4.78 | 0.89–25.54 | 0.066 |
| Platelet count <100,000/mm3 | 9.0 | 3.12–25.9 | <0.001* | 6.0 | 1.082–33.2 | 0.04* |
| Serum creatinine >1.5 mg/dl | 29.9 | 7.4–120.4 | <0.001* | 21.7 | 2.6–180.2 | 0.004* |
| AST, ALT or both >500 IU/L† | 7.7 | 3.3–17.9 | <0.001* | 6.0 | 1.15–31.2 | 0.03* |
Abbreviations: MODS Multiple Organ Dysfunction Syndrome, RR relative risk, CI confidence interval, † AST Aspartate aminotransferase, ALT Alanine aminotransferase; *statistically significant (P < 0.05)