Figure 5.

Effect of Sw FrIII (a) and Sw FrIV (b) on paw edema induced by carrageenan in rats. Before receiving a 0.1 ml injection of carrageenan (Cg, 500 μg/paw, ipl), rats received saline or Sw FrIII or Sw FrIV (2.5, 5 or 10 mg/kg). Diclofenac sodium (5 mg/kg) was injected s.c. Another group received only saline (s.c.) without Cg. Data are expressed as mean ± standard error of the mean of six rats per group. *P < 0.05 indicates significant difference from the diclofenac-treated group (ANOVA, Tukey's test)