Table 2.
Multivariate logistic regression analysis to examine variables associated with nephropathy, retinopathy, neuropathy, and CVD
| Nephropathy |
Retinopathy |
Neuropathy |
CVD |
|||||
|---|---|---|---|---|---|---|---|---|
| Model A | Model B | Model A | Model B | Model A | Model B | Model A | Model B | |
| OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | |
| Male | 1.39*** (1.26 to 1.53) | 1.43*** (1.30 to 1.58) | 0.81*** (0.74 to 0.90) | 0.75*** (0.68 to 0.83) | 1.14** (1.03 to 1.25) | 1.16** (1.05 to 1.28) | 1.71*** (1.50 to 1.96) | 1.70*** (1.49 to 1.95) |
| Age per 10-year | 1.12*** (1.07 to 1.18) | 1.11*** (1.05 to 1.17) | 0.89*** (0.85 to 0.94) | 0.81*** (0.77 to 0.86) | 1.48*** (1.40 to 1.56) | 1.53*** (1.45 to 1.62) | 1.78*** (1.65 to 1.92) | 1.77*** (1.64 to 1.91) |
| Duration per 10-year | 1.21*** (1.14 to 1.27) | 1.08** (1.02 to 1.14) | 1.89*** (1.79 to 2.00) | 1.81*** (1.71 to 1.92) | 1.31*** (1.24 to 1.38) | 1.14*** (1.08 to 1.21) | 1.26*** (1.18 to 1.35) | 1.18*** (1.10 to 1.27) |
| BMI per kg/m2 | 1.07*** (1.06 to 1.08) | 1.06*** (1.05 to 1.07) | 1.03*** (1.02 to 1.04) | 1.01* (1.00 to 1.03) | 1.05*** (1.04 to 1.06) | 1.04*** (1.02 to 1.05) | 1.04*** (1.02 to 1.05) | 1.03** (1.01 to 1.05) |
| HbA1c on target | 0.74*** (0.67 to 0.81) | 0.79*** (0.72 to 0.86) | 0.72*** (0.65 to 0.79) | 0.77*** (0.70 to 0.85) | 0.77*** (0.70 to 0.84) | 0.83*** (0.75 to 0.92) | 0.84** (0.74 to 0.95) | 0.88 (0.78 to 1.01) |
| BP on target | 0.67*** (0.61 to 0.74) | 0.68*** (0.62 to 0.75) | 0.85** (0.77 to 0.93) | 0.91 (0.82 to 1.00) | 0.90* (0.82 to 0.99) | 0.96 (0.87 to 1.06) | 0.93 (0.82 to 1.05) | 0.96 (0.85 to 1.10) |
| Lipids on target | 0.75*** (0.68 to 0.82) | 0.76*** (0.69 to 0.84) | 0.93 (0.84 to 1.02) | 1.01 (0.91 to 1.12) | 0.84*** (0.76 to 0.92) | 0.87** (0.79 to 0.96) | 1.11 (0.96 to 1.27) | 1.14 (0.99 to 1.31) |
| eGFR per 10 mL/min/1.73 m2 | 0.85*** (0.83 to 0.88) | 0.87*** (0.85 to 0.90) | 0.87*** (0.85 to 0.90) | 0.90*** (0.87 to 0.93) | 0.96** (0.93 to 0.99) | 1.00 (0.97 to 1.03) | 0.87*** (0.83 to 0.90) | 0.89*** (0.86 to 0.92) |
| Nephropathy | – | – | – | 1.99*** (1.80 to 2.21) | – | 1.58*** (1.43 to 1.75) | – | 1.26** (1.10 to 1.44) |
| Retinopathy | – | 1.99*** (1.80 to 2.21) | – | – | – | 2.70*** (2.43 to 2.99) | – | 1.44*** (1.25 to 1.66) |
| Neuropathy | – | 1.57*** (1.42 to 1.74) | – | 2.66*** (2.40 to 2.95) | – | – | – | 1.25** (1.09 to 1.43) |
Model A included sex, age, duration of diabetes, BMI, HbA1c on target, BP on target, lipids on target, and eGFR as covariates.
Model B included nephropathy, retinopathy, and neuropathy as covariates in addition to model A.
*p<0.05, **p<0.01, and ***p<0.0001.
BMI, body mass index; BP, blood pressure; CVD, cardiovascular diseases; eGFR, estimated glomerular filtration rate; HbA1c, glycated hemoglobin.