Table 3.
Linear mixed model estimates for the biomarkers and the eight domains of SF-36
| Domain | EC4d (log net MFI) |
EC3d (log net MFI) |
ECR1 (log net MFI) |
C3 (mg/dL) | C4 (mg/dL) | Anti dsDNA (units) | AntiC1q (units) |
|---|---|---|---|---|---|---|---|
| Physical function | −1.83±2.02 p=0.365 |
−1.01±1.54 p=0.513 |
3.43±2.21 p=0.121 |
−0.08±0.04 p=0.033 |
0.08±0.14 p=0.559 |
0.01±0.00 p=0.037 |
0.00±0.03 p=0.958 |
| Role Physical |
−6.96±2.00 p=0.001 |
−4.89±1.54 p=0.002 |
0.91±2.22 p=0.684 |
−0.06±0.04 p=0.148 |
0.13±0.14 p=0.358 |
0.01±0.01 p=0.101 |
−0.03±0.03 p=0.172 |
| Bodily pain |
−8.63±2.53 p=0.001 |
−6.34±1.94 p=0.001 |
1.98±2.9 p=0.495 |
−0.06±0.05 p=0.216 |
0.26±0.18 p=0.152 |
0±0.01 p=0.725 |
−0.02±0.03 p=0.562 |
| General health |
−6.64±1.3 p<0.001 |
−3.5±1.01 p=0.001 |
−1.57±1.45 p=0.280 |
−0.02±0.03 p=0.555 |
0.23±0.09 p=0.015 |
0.00±0.00 p=0.760 |
−0.01±0.02 p=0.594 |
| Vitality |
−5.81±1.67 p=0.001 |
−5.26±1.27 p<0.001 |
−0.59±1.85 p=0.748 |
0.02±0.03 p=0.502 |
0.22±0.12 p=0.058 |
0.00±0.00 p=0.765 |
−0.04±0.02 p=0.074 |
| Social functioning |
−8.44±2.14 p<0.001 |
−5.21±1.65 p=0.002 |
1.18±2.41 p=0.624 |
−0.03±0.04 p=0.461 |
0.16±0.15 p=0.313 |
0.01±0.01 p=0.151 |
−0.05±0.03 p=0.093 |
| Role emotional |
−4.5±2.22 p=0.043 |
−0.69±1.71 p=0.687 |
−3.85±2.44 p=0.116 |
−0.11±0.04 p=0.011 |
−0.24±0.16 p=0.127 |
0.01±0.01 p=0.247 |
−0.05±0.03 p=0.058 |
| Mental Health |
−6.72±1.47 p<0.001 |
−3.48±1.14 p=0.002 |
0.5±1.65 p=0.764 |
0.01±0.03 p=0.716 |
0.28±0.11 p=0.009 |
0.00±0.00 p=0.391 |
−0.05±0.02 p=0.005 |
Estimates with p values are given. EC4d, EC3d and ECR1 were log transformed as log net MFI.
MFI, mean fluorescent intensity; SF-36, short-form 36 questionnaires.