Table 2.

Minimal Clinical Diagnostic Criteria for Common Craniosynostosis (Adapted with permission from [1]).

Condition	Minimal diagnostic criteria
Apert syndrome	Craniosynostosis, midface hypoplasia, symmetrical syndactyly of hands and feet
Crouzon syndrome	Craniosynostosis, maxillary hypoplasia, shallow orbits, ocular proptosis, normal extremities
Muenke syndrome	Unilateral or bilateral coronal synostosis, absent or minimal hand/foot anomalies
Pfeiffer syndrome	Craniosynostosis, high forehead, maxillary hypoplasia, mild syndactyly of hands and/or feet, broad thumbs and/or great toe
Saerthre-Chotzen syndrome	Brachycephaly/plagiocephaly +/- evidence for craniosynostosis, high forehead, facial asymmetry, maxillary hypoplasia, brachydactyly, partial cutaneous syndactyly in some cases, thumb/great toe anomalies