Fig. 3.

Infection duration and overall nef gene diversity of STEP vaccine and placebo patients.

(a) The infection duration estimated by the shifted Poisson mixture model for 29 STEP vaccinees and 20 placebo patients with a single-strain infection. The horizontal line denotes the mean of each group and the box plots the first and third quartiles. Infection duration did not differ significantly between the single-strain vaccine and placebo groups (ANOVA, P = 0.52). (b) Nef gene diversity comparison between the 29 vaccine and 20 placebo patients. The overall nef gene sequence diversity was comparable among the two groups (ANOVA, P = 0.98).