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UCA1 overexpression and miR-27b knockdown confers MDR to gastric cancer cells. (A) ADR, DDP, and 5-FU IC50 in SGC-7901 cells after transfection of UCA1 expression vector or miR-27b inhibitors. (B, C) Representative images (B) and quantitation (C) of flow cytometric analysis of apoptotic SGC-7901 cells with the transfection of UCA1 expression vector or miR-27b inhibitors and then treated with 10 μg/mL ADR for 48 hours. ** p<0.01.
