Table I.

Demographic and neurological characteristics of HIE infants, hypothermia versus traditional care

Characteristic	Hypothermia (16)	Traditional care (11)	P
Male, No. (%)	8 (50)	4 (36)	.7
GA, wk, mean ± SE	38 ± 0.4	39 ± 0.5	.3
Birth weight, g, mean ± SE	3344 ± 219	3674 ± 263	.3
Head circumference, cm, mean ± SE	34 ± 0.5	35 ± 0.5	.3
Apgar score at 1 min, mean (range)	1 (0–3)	1(0–9)	.5
Apgar score at 5 min, mean (range)	4 (0–7)	1 (0–9)	.4
Sarnat stage 2, No. (%)	11 (69)	6 (55)	.7
Sarnat stage 3, No. (%)	5 (31)	5 (45)	.7
Initial EEG abnormality, No. (%)	15 (94)	8 (80)*	.5
Electrographic seizure, initial EEG, No. (%)	5 (31)	6 (60)*	.2
Clinical seizure, No. (%)	8 (50)	8 (80)	.2
MRI findings of HIE, No. (%)	11 (69)	11 (100)	.06
Basal ganglia-thalamic abnormality	9 (56)	10 (91)	.09
Brainstem abnormality	4 (25)	2 (18)	.7
Other abnormal findings†	4 (25)	3 (27)	.9
Normal MRI	1 (6)	0	1.0

EEG, electroencephalography; MRI, magnetic resonance imaging.

^*EEG not available for 1 patient.

^†MRI findings other than HIE changes included hemorrhage, volume loss, or fluid collections.