Table 1.
Effects of SAMe, taurine, betaine, and the combinations of three sulfur containing amino acids on body weight and liver weight in experimental mice
| Group | Treatments | BW (g) | LW (g) | LW/BW ratio |
|---|---|---|---|---|
| Control | Saline | 22.28 ± 0.68 | 0.85 ± 0.05a | 0.38 ± 0.02a |
| LPS | Saline | 22.10 ± 0.45 | 1.13 ± 0.03cd | 0.51 ± 0.01d |
| SAMe | 22.52 ± 1.27 | 1.15 ± 0.07cd | 0.51 ± 0.02d | |
| Tau | 22.70 ± 0.97 | 1.16 ± 0.05d | 0.51 ± 0.02d | |
| Bet | 21.00 ± 0.65 | 0.96 ± 0.05ab | 0.46 ± 0.02b | |
| SAMe + Tau | 21.07 ± 1.08 | 1.06 ± 0.08cd | 0.50 ± 0.03cd | |
| SAMe + Bet | 21.29 ± 0.30 | 1.03 ± 0.05bc | 0.48 ± 0.02bcd | |
| SAMe + Tau + Bet | 21.03 ± 1.19 | 0.99 ± 0.07b | 0.47 ± 0.01bc | |
| PolyI:C | Saline | 22.25 ± 0.34 | 0.97 ± 0.02b | 0.44 ± 0.01 |
| SAMe | 22.59 ± 0.61 | 0.97 ± 0.04b | 0.43 ± 0.02 | |
| Tau | 22.19 ± 0.78 | 0.97 ± 0.06a | 0.44 ± 0.01 | |
| Bet | 22.71 ± 0.70 | 0.99 ± 0.04b | 0.44 ± 0.01 | |
| SAMe + Tau | 22.43 ± 1.12 | 0.98 ± 0.05b | 0.44 ± 0.01 | |
| SAMe + Bet | 22.57 ± 0.43 | 0.93 ± 0.09a | 0.41 ± 0.04 | |
| SAMe + Tau + Bet | 21.91 ± 0.61 | 0.94 ± 0.05a | 0.43 ± 0.01 |
Values are presented as mean ± SEM (n = 5). SAMe, S-adenosylmethionine; Tau, taurine; Bet, betaine; BW, body weight; LW, liver weight; LPS, lipopolysaccharide; PolyI:C, polyinosinic-polycytidylic acid.
abcd
Values with different superscripted alphabets are significantly different at P < 0.01 level compared with control group.