Table 3.
Comparison of AUC values of test data set for single/combined marker(s) using logistic regression
| Marker | AUC | Probability | Cutoff from training | Specificity at the cutoff (%) | Sensitivity at the cutoff (%) |
|---|---|---|---|---|---|
| HE4 | 0.842 | 2.25E-13 | 0.1094199 | 89.33 | 57.53 |
| CEA | 0.681 | 6.60E-05 | 0.6434527 | 94.67 | 28.77 |
| RANTES | 0.829 | 1.83E-12 | 5.076444 | 92.00 | 0.00 |
| ApoA2 | 0.828 | 1.97E-12 | 5.60206 | 90.67 | 1.37 |
| TTR | 0.791 | 3.89E-10 | 5.630428 | 92.00 | 4.11 |
| sVCAM-1 | 0.698 | 1.48E-05 | 3.161243 | 82.67 | 5.48 |
| CEA, HE4 | 0.841 | 2.66E-13 | 0.5850375 | 86.67 | 57.33 |
| RANTES, ApoA1, TTR, sVCAM-1 | 0.942 | 4.47E-21 | 0.4779614 | 89.33 | 77.33 |
| CEA, HE4, RANTES, ApoA2, TTR, sVCAM-1 | 0.985 | 5.26E-25 | 0.357278 | 90.67 | 94.67 |
| CEA, HE4, RANTES, ApoA2, TTR, sVCAM-1, age | 0.988 | 2.71E-25 | 0.3700928 | 93.33 | 92.00 |
AUC, the area under the curve; HE4, human epididymis secretory protein 4; CEA, carcinoembryonic antigen; RANTES, regulated on activation, normal T cell expressed and secreted; ApoA2, apolipoprotein A2; TTR, transthyretin; sVCAM-1, secretory vascular cell adhesion molecule-1.