Figure 2.
Caveolin protein knockdown and BKPyV entry. (A) Cross-reactivity of siRNAs targeting caveolin 1 and caveolin 2. Individual siRNAs targeting caveolin 1 and an siRNA pool targeting caveolin 2 were transfected into RPTE cells. Caveolin expression at 2 days post infection was examined by Western blotting. (B) Caveolin protein knockdown does not affect BKPyV infection. RPTE cells were transfected with the indicated siRNAs. Viral infection and caveolin protein expression levels were examined by Western blotting at two days post infection. (C) RPTE cells were transfected with the indicated siRNAs. Viral infection and caveolin protein expression levels were examined by Western blotting at one day post infection.
