Fig 6. Combining immobilized and clustering motors.

Simulation outputs of MTOCs (grey) motility in the presence of a combination of diffusible tetrameric minus-ended motor complexes ($N_m^c={10}^4$, f₀ = 7 pN) with chromatin-centered gradient of immobilized motors ($N_m^i={10}^3$ motors/oocyte, f₀ = 7 pN) at (A) t = 0 and (B) t = 20 minutes. (C) The χ values of aster movement resulting from increasing densities of weak (f₀ = 2 pN) and strong (f₀ = 7 pN) clustering motors ($N_m^c={10}^3$ to 10⁵ motors/oocyte) in the presence of a gradient of immobilized motors with the same f₀ values ($N_m^i={10}^4$ for f₀ = 2 pN and $N_m^i={10}^3$ for f₀ = 7 pN). (D) The sum rank (R_s) based on the sum of square errors (ϵ) from χ distributions (grey) and % MTOCs captured in 20 minutes (black) from experiment are plotted in an ascending order, with the parameters of the density of immobilized motors ($N_m^i$) and diffusible motor complexes ($N_m^c$) plotted, assuming the f₀ is constant for both.