Table 3. MSP10 N-Terminal oligonucleotide and AuNPs were able to detect P. vivax in urine with higher sensitivity, specificity and lower cross-reactivity than C-Terminal oligonucleotide of MSP10.
Origin | MSP10 N-Terminal oligonucleotide Detection | MSP10 C-Terminal oligonucleotideDetection | |
---|---|---|---|
Urine Samples Positive for P. vivax | Iquitos, Peru | 26 | 20 |
(26/31: 84%) | (20/31: 65%) | ||
Urine Samples Positive for P. falciparum | Ghana | 3 | 5 |
(3/14: 21%) | (5/14: 36%) | ||
South American Negative Urine Samples | Peru | 1 | 1 |
(1/36: 3%) | (1:36: 3%) | ||
African Negative Urine Samples | Ghana | 0 | 0 |
(0/9: 0%) | (0/9: 0%) |