Table 2. Estimated recovery from 1 l of FV-hCD18 vector after each step of purification.
| Step | Volume of vector (ml) | Processing time | % of step recovery (average ± SEM)a | n |
|---|---|---|---|---|
| Heparin column | 333.3 | 5 hours | 69 ± 2.7 | 5 |
| TFF | 11.9 | 45 minutes | 89 ± 5.8 | 5 |
| 0.2 m filter | 11.9 | 15 minutes | 84 ± 4.5 | 5 |
| Ultracentrifugation | 0.2 | 2 hours | 48 ± 6.3 | 5 |
| Net recovery | 0.2 | 8 hoursb | 19 ± 3.1 | 5 |
Data represent mean and standard error of mean (SEM) of five independent experiments.
Total processing time.