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. Author manuscript; available in PMC: 2017 May 18.
Published in final edited form as: Xenotransplantation. 2016 May 18;23(3):222–236. doi: 10.1111/xen.12236

Table. 1.

Summary of lung failure mechanisms in the different treatment groups. The table shows that the loss of blood flow through the lungs (elevated PVR) was the predominant lung failure mechanism, followed by the development of trachea edema.

Control αGPIb DDAVP αGPIb + DDAVP αGPIIb/IIIa αGPIb + αGPIIb/IIIa
Total (n) 37 6 6 6 6 4
Failed lungs (n) 27 3 1 1 5 3
Rejection reason n (%) of failed lungs
Trachea edema 7 (19%) 2 (33%) - - 1 (17%) 1 (25%)
Loss of perfusate 2 (5%) - - - - -
Loss of blood flow 15 (41%) 1 (17%) 1 (17%) 1 (17%) 4 (67%) 2 (50%)
Oxygen failure 3 (8%) - - - - -

The table shows that the loss of blood flow through the lungs (elevated pulmonary vascular resistance) was the predominant lung failure mechanism, followed by the development of trachea edema.

DDAVP, desmopressin (1-desamino-8-d-arginine vasopressin).