Table 3.
| Toxicity | Grade 1 | Grade 2 | Grade 3 | Grade 4 | Grade 5 | SAE |
|---|---|---|---|---|---|---|
| Hematologic | ||||||
| Lymphopenia | 0 | 0 | 0 | 34 | 0 | No |
| Thrombocytopenia | 0 | 0 | 30 | 1 | 0 | No |
| Neutropenia | 0 | 0 | 11 | 21 | 0 | No |
| Leukopenia | 0 | 0 | 0 | 26 | 0 | No |
| Non-Hematologic | ||||||
| Hypophosphatemia | 0 | 0 | 5 | 1 | 0 | No |
| Hyperglycemia | 0 | 0 | 2 | 0 | 0 | No |
| Muscle Weakness | 0 | 0 | 1 | 0 | 0 | No |
| Bone Pain | 0 | 0 | 1 | 0 | 0 | No |
| Rash Maculo-papular | 0 | 0 | 1 | 0 | 0 | No |
| Hypotension | 0 | 0 | 2 | 0 | 0 | Yes |
| Muscle Weakness | 0 | 0 | 1 | 0 | 0 | No |
| Stroke | 0 | 1 | 0 | 0 | 0 | Yes |
| Renal Insufficiency | 1 | 0 | 0 | 0 | 0 | Yes |
| Atrial Fibrillation | 0 | 1 | 0 | 0 | 0 | Yes |
| Neutropenic Fever | 0 | 0 | 1 | 0 | 0 | Yes |
| Sepsis | 0 | 0 | 1 | 0 | 0 | Yes |