Table 3.

Multivariable Logistic Regression Analysis: Factors associated with ventilator-associated pneumonia (VAP) in mechanically ventilated children (N=1245)

Variable	Odds Ratio	95% CI	p
Age, months	1.00	0.96 - 1.01	0.99
BMI Z-score	0.99	0.90 - 1.12	0.94
Gender
Male	1.13	0.72 - 1.81	0.59
Female	Ref.
Diagnosis
Medical	1.31	0.77 - 2.21	0.31
Surgical	Ref.
Severity Level¶	1.52	0.86 - 2.67	0.17
Mechanical Ventilation >10 days	3.70	2.15 - 6.42	<0.001*
PICU >10 days	1.93	1.13 - 3.30	0.019*
Acid-suppressive Therapy	2.14	1.20 - 3.85	0.008*
Enteral Nutrition, days	1.12	0.95 - 1.32	0.21

PICU = pediatric intensive care unit, CI = confidence interval

^*statistically significant

^¶Severity level 4 vs. other grades.

³Severity of illness levels were corresponding to the quartiles of the Pediatric Index of Mortality (PIM) scores or Pediatric Risk of Mortality (PRISM) score for the cohort. A patient was considered Level 4 if his/her score was in the highest 4^th quartile of the group of patients who used the same scoring system.