Table 1.
Overall | STN | GPI | P value | |
---|---|---|---|---|
N | 33 | 20 | 13 | |
Age at Diagnosis (years) | 54.49 (8.69) | 23.20 (9.51) | 56.51 (7.16) | 0.51 |
Age at DBS (years) | 62.29 (9.00) | 60.88 (9.82) | 64.45 (7.40) | 0.42 |
PD Diagnosis to implantation (years) |
7.79 (2.55) | 7.69 (2.61) | 7.95 (2.56) | 0.67 |
Gender | ||||
M | 24(73%) | 15(75%) | 9(61%) | 1.0 |
F | 9(27%) | 5 (25%) | 4(39%) | |
Cognitive Status Above MCI |
25 (76%) | 17(85%) | 8 (62%) | 0.21 |
MCI | 8(24%) | 3 (15%) | 5 (38%) | |
UPDRS | ||||
"off" | 40.64 (11.10) | 43.20 (10.74) | 36.69 (10.88) | 0.12 |
"on" | 20.39 (8.09) | 20.50 (8.11) | 20.23 (8.39) | 0.84 |
Hoehn and Yahr score | 3.18(0.58) | 3.25(0.55) | 3.08(0.64) | |
2 | 3 (9%) | 1 (5%) | 2 (15%) | 0.58 |
3 | 21 (64%) | 13 (65%) | 8 (62%) | |
4 | 9 (27%) | 6 (30%) | 3 (23%) | |
Total LEDD | 1233.10 (573.86) | 1222.30 (625.46) | 1249.62 (508.20) | 0.91 |
Dopamine agonist LEDD | 207.42 (206.12) | 159.00 (158.34) | 281.92 (252.34) | 0.23 |
Legend: Patient demographics. Numerical values correspond to mean with standard deviation or percentages in parentheses. STN=Subthalamic nucleus, GPI=globus pallidus, DBS=Deep Brain Stimulation, PD=Parkinson’s disease, M=male, F=female, MCI=Mild Cognitive Impairment, LEDD=Levodopa equivalent daily dose. P values were calculated using the Wilcoxon rank sum test with the exception of values marked with a *. These were calculated using chi square analysis.