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. Author manuscript; available in PMC: 2017 Oct 15.
Published in final edited form as: Bioorg Med Chem. 2016 Apr 26;24(20):4779–4786. doi: 10.1016/j.bmc.2016.04.050

Figure 4.

Figure 4

Plot of -log IC50 (nM) vs −log k (s−1) illustrating the parabolic relationship between reactivity and cytotoxic activity and the placement of CImI in this relationship.