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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Eur Radiol. 2016 Apr 5;26(12):4239–4248. doi: 10.1007/s00330-016-4332-4

Table 2.

Comparison of 18F-FDG PET/STIR and for 18F-FDG PET/FSPGR for the detection of malignant lesions in children and young adults: Analysis based on 285 lesions at 2046 anatomical sites of 62 regions (nodal, extra-nodal and bone) assessed in 33 patients.

Regions # of regions Procedure # of lesions True Positive False Positive True Negative False Negative Sensitivity (%) Specificity (%) PPV (%) NPV (%) Accuracy (%)
Nodal Head/Neck 5 PET/FSPGR 50 50 0 50 0 100 100 100 100 100
PET/STIR 50 50 0 50 0 100 100 100 100 100
Chest 11 PET/FSPGR 82 82 0 249 0 100 100 100 100 100
PET/STIR 82 82 0 249 0 100 100 100 100 100
Axilla 2 PET/FSPGR 18 18 0 35 0 100 100 100 100 100
PET/STIR 18 18 0 35 0 100 100 100 100 100
Abdominal 7 PET/FSPGR 30 30 0 177 0 100 100 100 100 100
PET/STIR 30 30 0 177 0 100 100 100 100 100
Pelvic 8 PET/FSPGR 25 24 1 200 0 100 99.5 96.0 100 99.6
PET/STIR 25 24 1 200 0 100 99.5 96.0 100 99.6
Extra-nodal 10 PET/FSPGR 23 22 1 266 1 95.7 99.6 95.7 99.6 99.3
PET/STIR 23 22 1 266 1 95.7 99.6 95.7 99.6 99.3
Bone 19 PET/FSPGR 58 57 1 402 1 98.3 99.8 98.3 99.8 99.6
PET/STIR 57 57 0 403 1 98.3 100 100 99.8 99.8
Sum of all regions 62 PET/FSPGR 286 283 3 1380 2 99.3 99.8 99.0 99.9 99.7
PET/STIR 285 283 2 1381 2 99.3 99.9 99.3 99.9 99.8

PPV: Positive Predictive Value, NPV: Negative Predictive Value