Table I.

Distribution of the extended phenotypes of wheezing from 0 to 16½ years among female (n = 5973) and male (n = 6330) members of the study population

Phenotype	Female subjects, no. (%)∗	Male subjects, no. (%)∗	Mean probability difference†	P value, Wald test
Never/infrequent wheeze	3800 (63.6)	3499 (55.3)	0.01	.004
Preschool-onset remitting wheeze	1020 (17.1)	1333 (21.1)	0.03	.33
Midchildhood-onset remitting wheeze	444 (7.4)	442 (7)	0.06	.53
School-age–onset persisting wheeze	190 (3.2)	312 (4.9)	0.13	.0061
Late childhood–onset persisting wheeze	260 (4.4)	357 (5.6)	0.10	<.0001
Continuous wheeze	259 (4.3)	387 (6.1)	0.04	.26

^∗Most probable phenotype based on model estimated probabilities, including sex as a known class.

^†For each phenotype, the difference between male and female subjects of the probability of wheezing at each time point were calculated and then averaged.