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. 2016 Sep 27;5:39. doi: 10.1186/s40169-016-0120-7

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 5 — Serum S100A6 levels as prognostic biomarker for CCA. a Patients that succumbed to death showed a trend towards higher levels of S100A6 at admission to our hospital when compared to survivors (not significant). b, c Cox regression- and Kaplan–Meyer curve analyses revealed that those patients that displayed high S100A6 levels (e.g. S100A6 levels within the upper quartile of the CCA cohort) had a trend towards an impaired prognosis. d Postoperative S100A6 levels also depicted a trend towards a better survival in patients with low S100A6 concentrations. e, f Kinetics of S100A6 serum concentrations before/after surgery did not indicate the patients’ prognosis