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. 2016 Oct 6;10:41. doi: 10.3389/fninf.2016.00041

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Copyright © 2016 Lareo, Forlim, Pinto, Varona and Rodriguez.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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IPI histogram and qqplots resulting from executing the code-driven and the open-loop protocols, as compared to the control session. (A) IPIs discharged during the first control session (A dashed line) and the code-driven stimulation session (A solid line). (C) IPIs discharged during the second control session (C dashed line) and the open-loop stimulation session (C solid line). IPIs, represented on the X axis, were in the range between 0 and 400 ms and the probability, represented in the Y axis, was normalized. The qqplots represent the IPI distribution during control session vs. the IPI distribution during code-driven stimulation sessions (B) and open-loop sessions (D). In both qqplots the black line represents the reference line y = x. See an additional example in Figure S4.