Table 3.

Transplantation evaluation process

Hepatology evaluation	Definition of the severity and etiology of the liver disease and its prognosis (MELD, Child–Pugh score, portal hypertension and its complication)
Laboratory testing	Bilirubin (total and indirect), GOT (AST), GPT (AST), γGT, alkaline phosphatase, synthetic function (prothrombin time, INR, albumin), glucose, lipid and iron metabolism, renal function, thyroid parameters, viral hepatitis A–E, ceruloplasmin, alpha 1‑antitrypsin (genotyping), tumor markers, autoimmune parameters (ANA, AMA, SMA, LKM)
Hepatic imaging	Sonography with Doppler, MS-CT/dynamic MRT (exclusion or staging of HCC, splanchnic vessel evaluation)
Cardiopulmonary evaluation	Spirometry, arterial blood gases, (contrast)echocardiography, individual: stress-echocardiography, coronary CT, coronary angiography (CAG)
Psychosocial evaluation	Including assessment of alcohol and other addictions
Extrahepatic malignancies	Gastro- and colonoscopy, chest X‑ray (chest CT in case of special risk factors [e. g. nicotine]), ENT, gynecology/urology, dermatology
Infectiologic evaluation	CMV, EBV, tuberculosis screening (Interferon Gamma Release Assay, IGRA)
Anesthesiologic risk assessment
Surgical risk assessment

MELD Model for End-stage Liver Disease, AST Aspartat-Aminotransferase, GOT Glutamat-Oxalacetat-Transaminase, ALT Alanin-Aminotransferase, GPT Glutamat-Pyruvat-Transferase, ANA Antinuclear Antibodies, AMA Antimitochondrial Antibodies, SMA Smooth Muscle Antibodies, LKM Liver Kidney Microsomal Antibodies, MS‑CT multi-sclice Computed Tomography, CMV cytomegalo virus, EBV epstein barr virus, MRT (MRI) Magnetic Resonance Tomography (Imaging)