Table 1.
Baseline Characteristics of the Study Participants in the POUNDS Lost (n = 711) Across Tertiles of Baseline Taurine Levels
| Tertiles of Baseline Taurine Levels |
|||
|---|---|---|---|
| T1 (n = 237) | T2 (n = 237) | T3 (n = 237) | |
| Age, y | 50.44 ± 9.11 | 51.46 ± 9.16 | 50.86 ± 9.57 |
| Female, n (%) | 152 (64.1) | 132 (55.7) | 151 (63.7) |
| Ethnic group, n (%) | |||
| White | 188 (79.3) | 186 (78.5) | 193 (81.4) |
| Black | 36 (15.2) | 39 (16.5) | 33 (13.9) |
| Hispanic, Asian, or other | 13 (5.5) | 12 (5.1) | 11 (4.6) |
| Low-fat diets, n (%) | 138 (58.2) | 110 (46.4) | 121 (51.1) |
| Average-protein diets, n (%) | 117 (49.4) | 124 (52.3) | 134 (56.5) |
| T2D GRS, n of risk alleles | 34.05 ± 4.21 | 33.86 ± 4.19 | 34.09 ± 4.75 |
| Baseline taurine, μmol/L | 1.19 (0.3) | 1.63 (0.2) | 2.09 (0.3) |
| Height, cm | 168.00 ± 8.77 | 169.12 ± 8.81 | 168.74 ± 8.83 |
| Baseline BMI, kg/m2 | 32.34 ± 3.63 | 32.69 ± 4.03 | 32.92 ± 3.93 |
| Baseline weight, kg | 91.65 ± 14.9 | 93.86 ± 15.77 | 94.12 ± 15.84 |
| Baseline fasting glucose, mg/dL | 91.22 ± 12.16 | 92.78 ± 12.13 | 91.28 ± 10.69 |
| Baseline fasting insulin, μU/L | 9.80 (6.5) | 10.60 (9.7) | 11.10 (9.1) |
| Baseline HOMA-IR | 2.17 (1.7) | 2.48 (2.4) | 2.51 (2.2) |
| Baseline HOMA-B | 125.33 (95.9) | 131.20 (98.7) | 144.77 (124.9) |
Abbreviations: BMI, body mass index; T1, tertile 1; T2, tertile 2; T3, tertile 3.
Data are presented as mean ± sd or n (%), except for taurine, fasting insulin, HOMA-IR, and HOMA-B presented as median (interquartile range).
The χ2 test was used for categorical variables and general linear regression with covariates of age (except for age), sex (except for sex), and weight (except for weight) for continuous variables (except for baseline taurine). No statistical significant results were found (all P > .05).