Table 3.

Percentage Difference in Bone Outcomes per 10 Years of Difference in Timing of Period Cessation (Natural/Surgical), Adjusted for Type of Menopause, and Then Additionally Adjusted for Current Height and Weight

	Model 1			Model 2
	Adjusted for Type of Menopause			Model 1 + Adjusted for Current Height and Weight
	Difference, %	95% CI	P Value	Difference, %	95% CI	P Value
Diaphysis CSA (n = 562)
Age at natural menopause	2	−1.6 to 5.7	.3	0.8	−2.5 to 4.1	.6
Age at hysterectomy	−1.3	−4.6 to 2.1	.5	−0.2	−3.2 to 2.8	.9
Medullary CSA (n = 561)
Age at natural menopause	−4.8	−13.9 to 4.4	.3	−6.1	−15.1 to 2.8	.2
Age at hysterectomy	1.7	−6.7 to 10.1	.7	3	−5.2 to 11.3	.5
Total vBMD (n = 555)
Age at natural menopause	6	0.5–11.5	.03	5.9	0.5–11.4	.03
Age at hysterectomy	0.8	−4.2 to 5.8	.8	0.7	−4.3 to 5.6	.8
Trabecular vBMD (n = 554)
Age at natural menopause	8.2	1.3–15.1	.02	8.2	1.4–15.0	.02
Age at hysterectomy	0.1	−6.2 to 6.4	>.9	−0.2	−6.4 to 6.1	>.9
Cortical vBMD (n = 563)
Age at natural menopause	0.5	−0.4 to 1.4	.3	0.5	−0.4 to 1.4	.3
Age at hysterectomy	−0.2	−1.1 to 0.6	.6	−0.2	−1 to 0.6	.6
Polar SSI (n = 563)
Age at natural menopause	3.7	−1.7 to 9.1	.2	2.1	−2.8 to 6.9	.4
Age at hysterectomy	−2.8	−7.7 to 2.1	.23	−1.4	−5. to 3.1	.5
Lumbar spine aBMD (n = 703)
Age at natural menopause	9.3	5.3–13.3	<.001	8.8	5.1–12.6	<.001
Age at hysterectomy	1.8	−2.0 to 5.6	.4	2.29	−1.3 to 5.8	.2
Total hip aBMD (n = 700)
Age at natural menopause	6.7	3.2–10.3	<.001	6.4	3.4–9.4	<.001
Age at hysterectomy	−0.04	−3.3 to 3.2	>.9	0.4	−2.4 to 3.2	.8