Table 1.

Minimal inhibitory concentration (MIC) and minimal fungicidal concentration (MFC) of the Origanum majorana Linn. essential oil and itraconazole against Sporothrix brasiliensis and Sporothrix schenckii.

Origin of the isolates of Sporothrix schenckii complex	Origanum majorana L. (mg/mL)						Itraconazole (μg/mL)
	MIC			MFC			MIC			MFC
	Range	50%	90%	Range	50%	90%	Range	50%	90%	Range	50%	90%
Sporothrix brasiliensis
Humans (n: 3)	≤2.25–4.5	–	–	≤2.25–4.5	–	–	≤0.03–0.5	–	–	≤0.03 to 2	–	–
Dogs (n: 6)	≤2.25–4.5	≤2.25	≤2.25	≤2.25–18	4.5	9	0.5–8	1	2	1 to >16	2	16
Cats (n: 8)	≤2.25–9	≤2.25	4.5	≤2.25–9	4.5	9	≤0.03–16	2	16	0.25 to >16	2	>16
Overall (n: 17)	≤2.25–9	≤2.25	4.5	≤2.25–18	4.5	9	≤0.03–16	2	8	≤0.03 to >16	2	>16
Sporothrix schenckii
IOC 1226 (n: 1)	≤2.25	–	–	≤2.25	–	–	1	–	–	8	–	–
Overall (n: 18)	≤2.25–9	≤2.25	4.5	≤2.25–18	4.5	9	≤0.03–16	1	16	≤0.03 to >16	2	>16

50%, MIC/MFC at which 50% of isolates were inhibited/eliminated; 90%, MIC/MFC at which 90% of isolates were inhibited/eliminated.