Table 3.

Discriminatory Metabolites Comparison Between Subject Cohorts.

Discriminatory metabolite	HCC median (arbitrary units)	Cirrhosis median (arbitrary units)	P-values
↑ Carnitine (3.24 ppm)	1.16 × 107	9.37 × 106	0.31
↑ Formate (8.5 ppm)	6.36 × 106	3.13 × 106	0.44
↓ Citrate doublet (2.56 ppm)	4.65 × 107	7.33 × 107	0.21
↓ Citrate doublet (2.68 ppm)	5.39 × 107	7.20 × 107	0.25
↓ Hippurate (3.97 ppm)	4.25 × 107	4.68 × 107	0.52
↓ Hippurate (7.56 ppm)	3.94 × 106	4.45 × 106	0.69
↓ p-cresol sulfate (2.35 ppm)	1.15 × 107	2.61 × 107	0.06*
↓ p-cresol sulfate (7.21 ppm)	6.68 × 106	1.32 × 107	0.04*
↓ Creatinine methyl (3.05 ppm)	4.50 × 108	5.01 × 108	0.26
↓ Creatinine methylene (4.06 ppm)	2.83 × 108	3.62 × 108	0.03*

^*P-values calculated using Mann–Whitney tests of significance.