Table 2.
Effects of ointment formulations of M. annua and T. purpurea on various biochemical parameters of tissues with dead-space wound in rats
| Groups |
Hydroxyproline
(mg/g tissue) |
Protein content
(mg/g tissue) |
Granuloma dry
weight (mg) |
|---|---|---|---|
| Control (Base) | 17.57 ± 0.64 | 32.63 ± 1.15 | 30.64 ± 1.02 |
| TPF-A Ointment (5% w/w) | 36.82 ± 1.21* | 58.54 ± 2.45* | 52.52 ± 2.14* |
| MAF-C Ointment (5% w/w) | 41.62 ± 2.03* | 56.24 ± 1.81* | 56.26 ± 1.52* |
| PONG Ointment (0.2% w/w) | 19.69 ± 0.43 | 31.18 ± 1.54 | 31.77 ± 1.18 |
| PONG Ointment (0.5% w/w) | 29.28 ± 1.81* | 41.64 ± 1.62* | 47.28 ± 1.63* |
| LUT Ointment (0.2% w/w) | 20.17 ± 0.97 | 34.89 ± 1.27 | 33.16 ± 1.20 |
| LUT Ointment (0.5% w/w) | 28.61 ± 1.25* | 44.72 ± 1.60* | 45.30 ± 1.84* |
| Povidone Iodine Ointment (5% w/w) | 43.26 ± 1.79* | 62.89 ± 2.10* | 57.85 ± 1.64* |
Values represent Mean ± S.D (n = 6).
*
p<0.01, when each treated group was compared with control and reference group. TPF-A: ethyl acetate fraction of T. purpurea; MAF-C: methanol soluble fraction of M. annua; PONG: Pongamol; LUT: Luteolin