Table 1. Associations and Influence of A/B/O, Lewis, and secretor blood types among children with the risk of rotavirus infection.
| Status | No. (%) of RV positive | No. (%) of RV/NoV† negative | OR (95% CI), P value | No. (%) of health control | OR (95% CI), P value |
|---|---|---|---|---|---|
| Blood type | n = 75 | n = 151 | N = 226, ^P = 0.384 | n = 159 | N = 234, ^P = 0.672 |
| A | 22 (29.3) | 47 (31.1) | 0.919 (0.502–1.682), 0.878 | 35 (22.0) | 1.471 (0.789–2.741),0.254 |
| B | 17 (22.7) | 44 (29.1) | 0.713 (0.374–1.358), 0.324 | 39 (24.5) | 0.902 (0.471–1.728), 0.870 |
| O | 33 (44.0) | 50 (33.1) | 1.587 (0.899–2.801), 0.143 | 79 (49.7) | 0.796 (0.458–1.382),0.484 |
| AB | 3 (4.0) | 10 (6.6) | 0.588 (0.157–2.202),0.552 | 6 (3.8) | 1.063 (0.258–4.369), 1.000 |
| Lewis status | n = 75 | n = 151 | N = 226, ^P = 0.004** | n = 159 | N = 234, ^P = 0.000** |
| Leb+/Ley+ | 63 (84.0) | 132 (87.4) | 1.198 (0.673–1.21), 0.539 | 134 (84.3) | 0.979 (0.462–2.075), 1.000 |
| Lea+/Lex+ | 0 (0.0) | 10 (5.6) | 0.653 (0.592–0.719), 0.033* | 20 (12.6) | 0.874 (0.824–0.927), 0.001** |
| Lea+b+/Lex+y+ | 12 (16.0) | 9 (6.0) | 3.005 (1.205–7.494),0.026* | 5 (3.1) | 5.869 (1.985–17.339), 0.001** |
| Secretor status§ | n = 75 | n = 151 | N = 226, ^P = 0.033* | n = 159 | N = 234, ^P = 0.001** |
| Secretor | 75 (100) | 141 (93.4) | 1.531 (1.39–1.69),0.033* | 139 (87.4) | 1.144 (1.079–1.214), 0.001** |
| Nonsecretor | 0 (0) | 10 (6.6) | 0.653 (0.592–0.719), 0.033* | 20 (12.6) | 0.874 (0.824–0.927), 0.001** |
†NoV samples were excluded from patients without RV infection; Unadjusted odds ratios (OR) and 95% confidence intervals (CIs); §Leb+/Ley+ and Lea+b+/Lex+y+ were grouped into secretor and Lea+/Lex+ were grouped into nonsecretor; ^P: significance test of proportion of different HBGA phenotype between RV positive group and control group; *P < 0.05; **P < 0.01.