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. 2016 Oct 6;6:34909. doi: 10.1038/srep34909

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Copyright © 2016, The Author(s)

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(a) Intraperitoneal pyruvate tolerance test performed at 24 h of BHB infusion. (b) Area under curve of plasma glucose levels during the Pyruvate tolerance test. Glycemia was measured during the 2 h following an intraperitoneal load of pyruvate which stimulates endogenous glucose production. Data represent the mean ± SEM with n = 6 animals per condition and were statistically analyzed with a two-way ANOVA for (a) and an unpaired Student t-test for (b). *p < 0.05 vs. NaCl; **p < 0.01 vs. NaCl; ***p < 0.001 vs. NaCl. a.u., arbitrary units; AUC, area under the curve.