Table 1.

Inhibitors of promiscuous targets.

target	compound class	references
DprE1	1,3-benzothiazin-4-ones (BTZs) (covalent)	[22,27]
DprE1	benzoquinoxaline (covalent)	[28]
DprE1	dinitrobenzamides (covalent)	[29]
DprE1	nitro-substituted triazole (covalent)	[25]
DprE1	benzothiazoles (covalent)	[30]
DprE1	benzothiazole-thiophene (non-covalent)	[31]
DprE1	2-carboxyquinoxalines (non-covalent)	[32]
DprE1	1,4-azaindole (non-covalent)	[33]
DprE1	pyrazolopyridone (non-covalent)	[34]
MmpL3	ethylene diamines	[20]
MmpL3	1,5-diarylpyrrole BM212	[35]
MmpL3	benzimidazole C215	[25]
MmpL3	tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamides	[26,36]
MmpL3	N-benzyl-6′,7′-dihydrospiro[piperidine-4,4′-thieno[3,2-c]pyrans	[36]
MmpL3	indolecarboxamides	[37,38]
MmpL3	adamantyl ureas	[39]
MmpL3	spiropiperidines	[40]
Pks13	thiophenes	[41–43]
Pks13	benzofurans	[26]
QcrB	imidazo[1,2-a]pyridine amides (IPA)	[21,44–47]
QcrB	imidazo[4,5-c]pyridines	[47]
QcrB	piperazine-pyrazole	[47]
QcrB	triazolo[3,4-b][1,3,4]thiadiazole	[47]
QcrB	oxoquinolines	[47]
QcrB	lansoprazole sulphide	[48]