Table 1.
Anthropometric and demographic characteristics of enrolled controls and remaining women and their children in the two datasets
| Characteristic* | Dataset A |
Dataset B |
||
|---|---|---|---|---|
| Controls | Remaining cohort† | Controls | Remaining cohort‡ | |
| Women | ||||
| Year of pregnancy | 2004-2006 | 2004-2006 | 1987-1990 | 1987-1990 |
| Number | 101 | 3961 | 118 | 25,030 |
| Education (year)§, ** | 14.0 (2.1) | 13.9 (3.8) | 13.3 (1.8) | 13.0 (2.0) |
| Hollingshead Score | 3.4 (1.1) | ND | 3.5 (0.6) | ND |
| Age at delivery (year)§,** | 30 (5) | 28 (6) | 28 (4) | 26 (5) |
| GA at screening (week)** | 17 (1) | 17 (1) | 17 (1) | 17 (1) |
| Weight at screening (kg) | 77 (18) | 75 (18) | 66 (13) | 67 (14) |
| BMI at screening (kg/m2) | 28.3 (6.2) | 27.8 (6.4) | 24.6 (4.6) | NA |
| BMI >30 (%) | 29.7 | 29.3 | 10.2 | NA |
| Primiparous (%)§ | 33.7 | 46.5 | 35.0 | 49.0 |
| Married at delivery (%) | 75.2 | 67.0 | 92.0 | 83.0 |
| Smoked during pregnancy (%) | 9.3 | 15.8 | 17.0 | 21.0 |
| Caucasian (%) | 98.9 | 97.4 | 100.0†† | 98.4-98.7‡‡ |
| Offspring | ||||
| Males (%)§,** | 47.5 | 51.6 | 41.7 | 52.6 |
| Birthweight mean (g) | 3533 (442) | 3497 (454) | 3532 (471) | 3495 (504) |
| Range | 2608-5358 | 2520-5613 | 1870-5075 | 1503-6039 |
| GA at delivery (week) | 39.1 (1.2) | 39.2 (1.2) | 40.0 (2) | 40.0 (2) |
| 5 minute Apgar Score | 9.0 (0.4) | 8.9 (0.6) | 9.0 (1) | 9.0 (1) |
| Age at testing (year) | 2.4 (0.4) | ND | 8.0 (1) | ND |
BMI, body mass index; NA, not available; ND, not done; GA, gestational age
Data are presented as mean (SD) unless otherwise noted
Euthyroid women, free T4 10th-90th centiles, who met study inclusion criteria (viable singleton pregnancy, gestation ≥36 weeks at delivery; infants with no congenital abnormality and birthweight >2500 g), but were not enrolled as matched controls
Euthyroid women with viable singleton pregnancies and infant birthweight ≥1500 g, who were not identified as cases or enrolled as matched controls
Variable used in matching controls with identified cases in Dataset A
Variable used in matching controls with identified cases in Dataset B
Data were available for 113 women
Maine's population was 98.7% Caucasian in 1980 and 98.4% in 1990 (www.census.gov)