Table 4.
Multivariable linear regression analysis for the delta SOFA and in-hospital length of stay
| Variable | Regression coefficient | Standard error | P-value |
|---|---|---|---|
| Analysis for the delta SOFA | |||
| Timely antibiotic use | 0.73 | 0.36 | 0.04 |
| APACHE II score | 0.06 | 0.02 | <0.01 |
| Initial serum lactate | -0.29 | 0.06 | <0.01 |
| ScvO2 ≥ 70% achieved | 1.20 | 0.35 | <0.01 |
| Analysis for in-hospital LOSa) | |||
| Timely antibiotic use | -0.28 | 0.08 | <0.01 |
| APACHE II score | 0.01 | 0.01 | 0.06 |
| Chronic renal disease | 0.36 | 0.18 | 0.05 |
| Chronic hepatic disease | 0.39 | 0.13 | <0.01 |
| Malignancy | 0.22 | 0.08 | 0.01 |
| CVP≥8 mmHg achieved | 0.19 | 0.08 | 0.02 |
SOFA, Sequential Organ Failure Assessment; APACHE, Acute Physiology and Chronic Health Evaluation; ScvO2, central venous oxygen saturation; LOS, length of stay; CVP, central venous pressure.
a)
The In-hospital LOS values were log transformed in order to obtain a normal distribution.