Table 2. Correlation of Plasma Macrophage Migration Inhibitory Factor Levels with Bone Mineral Density and Bone Turnover Markers.

Variable	Unadjusted		Age and BMI adjusted		Multivariable adjusted
	γ	P valuea	γ	P valueb	γ	P valuec
Bone mineral density, g/cm2
Lumbar spine	–0.327	<0.001	–0.335	<0.001	–0.317	<0.001
Femoral neck	–0.224	<0.001	–0.236	<0.001	–0.223	0.001
Total femur	–0.229	<0.001	–0.245	<0.001	–0.232	<0.001
Bone turnover markersd
Osteocalcin	0.186	0.015	0.189	0.014	0.187	0.017
CTX	0.217	0.001	0.218	0.001	0.196	0.004

Values are statistically significant.

BMI, body mass index; CTX, C-terminal telopeptide of type I collagen.

^aP values were determined by Pearson's correlation analysis; ^bP values were determined by partial correlation analysis adjusted for age and BMI; ^cP values were determined by partial correlation analysis adjusted for age, BMI, current smoking, alcohol intake (≥3 units/day), exercise status (≥30 min/day), parental history of osteoporotic fracture, years since menopause, and 25-hydroxyvitamin D₃; ^dMacrophage migration inhibitory factor and bone turnover markers were log-transformed because their distributions were positively skewed.