Table 4. Multiple Logistic Regression Analyses to Determine the Ability of Plasma MIF Levels to Predict Risk of Osteoporosis.

	OR (95% CI)a	P value
Unadjusted	1.387 (1.065–1.806)	0.015
Age and BMI adjusted	1.371 (1.051–1.788)	0.020
Multivariable adjusted	1.319 (1.007–1.729)	0.044

Values are statistically significant. Multivariable factors included age, BMI, current smoking, alcohol intake (≥3 units/day), exercise status (≥30 min/day), parental history of osteoporotic fracture, years since menopause, and 25-hydroxyvitamin D₃.

MIF, macrophage migration inhibitory factor; OR, odds ratio; CI, confidence interval; BMI, body mass index; SD, standard deviation.

^aPer SD increment in plasma MIF levels.