Table 1.
Characteristics of subjects
| Placebo (n = 19) | Q10-300 (n = 20) | |
|---|---|---|
| males (n, %) | 12 (63.2 %) | 15 (75.0 %) |
| age (y) | 61.5 ± 11.0 (62.0)a | 59.7 ± 8.3 (58.5) |
| SBP (mmHg) | 133.8 ± 18.0 (134.0) | 124.8 ± 19.3 (119.5) |
| DBP (mmHg) | 77.9 ± 11.2 (78.0) | 76.9 ± 12.3 (76.0) |
| waist circumference (cm) | 89.1 ± 7.8 (88.0) | 86.7 ± 10.2 (88.5) |
| waist hip ratio | 0.92 ± 0.05 (0.91) | 0.94 ± 0.16 (0.94) |
| BMI (kg/m2) | 24.7 ± 3.2 (24.5) | 23.1 ± 2.6 (22.8) |
| current smokerb, n (%) | 6 (31.6 %) | 5 (25.0 %) |
| drinks alcoholc, n (%) | 3 (15.8 %) | 3 (15.0 %) |
| Exercised, n (%) | 9 (47.4 %) | 8 (40.0 %) |
| Hepatitis B, n (%) | 14 (73.7 %) | 12 (60.0 %) |
| Hepatitis C, n (%) | 4 (21.1 %) | 7 (35.0 %) |
| Cirrhosis, n (%) | 6 (31.6 %) | 5 (25.0 %) |
| Recurrence, n (%) | 3 (15.8 %) | 4 (20.0 %) |
| Hematology | ||
| BUN (mg/dL) | 15.5 ± 4.9 (15.0) | 17.1 ± 9.2 (15.5) |
| creatinine (mg/dL) | 0.8 ± 0.3 (0.8) | 0.9 ± 0.3 (0.9) |
| GOT (IU/L) | 35.2 ± 24.8 (27.0) | 40.4 ± 23.0 (31.5) |
| GPT (IU/L) | 44.8 ± 36.6 (38.0) | 55.5 ± 39.8 (45.5) |
| TC (mg/dL) | 162.7 ± 36.4 (148.0) | 162.1 ± 32.7 (156.0) |
| TG (mg/dL) | 95.3 ± 42.3 (87.0) | 93.4 ± 29.9 (92.5) |
| LDL-C (mg/dL) | 100.4 ± 32.3 (90.0) | 102.3 ± 32.8 (100.0) |
| HDL-C (mg/dL) | 50.6 ± 11.6 (50.0) | 49.2 ± 12.4 (47.5) |
| TC / HDL-C | 3.3 ± 1.0 (2.9) | 3.5 ± 1.0 (3.5) |
| Dietary intake | ||
| Energy (kcal/d) | 1608.5 ± 334.5 (1531.2) | 1686.5 ± 460.8 (1655.8) |
| Protein (g/d) | 65.9 ± 17.9 (68.0) | 66.2 ± 21.2 (66.8) |
| % of total calories | 16.6 % | 15.7 % |
| Fat (g/d) | 49.5 ± 23.9 (48.2) | 50.6 ± 16.1 (51.7) |
| % of total calories | 26.6 % | 26.8 % |
| carbohydrate (g/d) | 228.6 ± 40.8 (227.0) | 251.1 ± 89.6 (238.6) |
| % of total calories | 57.2 % | 57.9 % |
| PUFA (g/d) | 15.6 ± 11.8 (13.0) | 13.8 ± 8.6 (11.1) |
| MUFA (g/d) | 15.1 ± 9.5 (11.9) | 15.3 ± 6.6 (15.6) |
| SFA (g/d) | 12.8 ± 8.0 (10.3) | 14.2 ± 5.7 (14.3) |
| vitamin A (μg R.E./d) | 3216.8 ± 4244.7 (1188.1) | 3204.2 ± 3705.5 (1110.4) |
| vitamin E (mg α-T.E./d) | 421.6 ± 727.1 (21.5) | 615.0 ± 989.3 (10.8) |
| cholesterol (mg/d) | 250.0 ± 163.8 (238.2) | 231.8 ± 117.6 (197.8) |
| dietary fiber (g/d) | 13.0 ± 6.5 (11.9) | 10.9 ± 6.1 (9.7) |
BMI body mass index, BUN blood urea nitrogen, GOT glutamic oxaloacetic transaminase, HCC hepatocellular carcinoma, HDL-C high-density lipoprotein-cholesterol, LDL-C low density lipoprotein-cholesterol, MUFA monounsaturated fatty acid, PUFA polyunsaturated fatty fat, SFA saturated fatty acid, TC total cholesterol, TG triglyceride
ameans ± SD (medians)
bcurrent smoker: individuals currently smoking one or more cigarettes per day
cdrinks alcohol: individuals drinking one or 1 more alcoholic drinks per day regularly
dexercise: individuals who exercise regularly at least 3 times every week