Table 3.
Midazolam (n=58) | Dexmedetomidine (n=58) | P-value | |
---|---|---|---|
Baseline | |||
Systolic blood pressure (mmHg) | 141±18 | 144±16 | 0.377 |
Mean blood pressure (mmHg) | 105±14 | 105±13 | 0.946 |
Heart rate (beats/min) | 73±12 | 74±13 | 0.853 |
Bispectral index | 95±4 | 95±4 | 0.249 |
Lowest | |||
Systolic blood pressure (mmHg) | 103±11 | 115±16 | <0.001 |
Mean blood pressure (mmHg) | 76±10 | 84±11 | <0.001 |
Heart rate (beats/min) | 58±9 | 52±7 | <0.001 |
Bispectral index | 67±10 | 62±11 | 0.011 |
Changes (%) | |||
Systolic blood pressure | 27±10 | 20±11 | <0.001 |
Mean blood pressure | 26±11 | 20±11 | 0.001 |
Heart rate | 19±10 | 29±11 | <0.001 |
Bispectral index | 29±11 | 34±12 | 0.030 |
Values are means ±SDs. Changes, (baseline-lowest)/baseline*100.